Found 81 matching trials
A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor Tissue PHASE2 This clinical study investigates the anti-inflammatory and anti-cancer prop...
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Linkou Chang Gung Memorial Hospital
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PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer PHASE2 In this open-label phase II study, patients will be scheduled for neoadjuva...
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651 Dongfeng Road East
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Rectal Cancer CTC Trial NA This prospective, multi-centre, randomised clinical trial aims to compare t...
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University Hospital Olomouc
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Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for Locally Advanced Mid-low Rectal Cancer N/A It is a single-center, retrospective, controlled study to investigate the e...
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Beijing Friendship Hospital, Capital medical University
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Neoadjuvant Chemoradiotherapy Followed by Chemotherapy With or Without Tislelizumab for Resectable Ultra-low Rectal Cancer: The RELIEVE-02 Study PHASE3 This open-label, multicenter, randomized controlled trial involved 154 pati...
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Multiple Locations
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Efficacy and Safety of Conventional Neoadjuvant Therapy Versus Total Neoadjuvant Therapy in Older Patients With Locally Advanced Rectal Cancer NA The SHAPERS study is a multicentre, open-label, randomised, pragmatic clini...
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KORTUC (KRC-01) Plus Radiotherapy for Organ Preservation in Rectal Cancer PHASE2 This phase II clinical trial is evaluating whether adding KRC-01 injections...
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Short-course Radiotherapy in TNT Combined With Enlonstobart for pMMR LARC PHASE2 Efficacy and safety of short-course radiotherapy in total neoadjuvant thera...
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Hebei Medical University Fourth Hospital
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Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer PHASE2 This single-arm trial will explore the efficacy and safety of long-course n...
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Active Not Recruiting
Location
Hebei Medical University Fourth Hospital
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Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer PHASE2 The addition of durvalumab to total neoadjuvant therapy (TNT) in locally ad...
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